It works similarly to other anthelmintic drugs like ivermectin and milbemycin by interfering with important neurotransmissions in parasites so that they become paralyzed and die.
Moxidectin injection for dogs.
In a laboratory study 16 beagle dogs implanted with adult heartworms d.
The product label for proheart 12 cites an alarmingly long list of adverse events of proheart 6.
Moxidectin is a drug that is used to treat parasites in dogs cats and large farm animals.
Zoetis knows moxidectin can be harmful to dogs.
The injection site that resolved spontaneously within 24 hours of administration.
It has recently been made available as a 10 percent moxidectin injection in 20 ml vials.
Moxidectin is also available in combination products as with advantage multi.
The safety of proheart 12 ph 12.
In a laboratory effectiveness study dogs with 4 and 6 month old heartworm infections administered moxidectin microspheres at a dose of 0 17 mg kg experienced vomiting lethargy and bloody diarrhea.
This is a topical solution product to be applied on the skin every month.
At 119 days post infection 56 days post moxidectin treatment no adverse clinical signs and no gross pathological effects were.
Food and drug administration s center for veterinary medicine announced today the approval of proheart 12 moxidectin extended release injectable suspension for dogs 12.
Cydectin injectable is specially formulated to allow moxidectin to be absorbed from the site of injection and distributed internally to the areas of the body affected by endo and or ectoparasitism.
And in case you missed it there s 3 times as much moxidectin in proheart 12 as proheart 6 so side effects are likely to be greater this is the exact list of adverse events on the label.
Moxidectin is available in 30 mcg 68 mcg and 136 mcg tablets.
Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones.
Immitis received either proheart 12 at 1 5 mg kg body weight 3x 8 dogs or a saline injection control 8 dogs.
Just 1 shot of proheart 6 from your veterinarian provides your dog with 6 months of protection and gives you 6 months peace of mind.
He s your best friend.
The proheart 12 injection works similarly to proheart 6 but instead of providing heartworm protection for six months it will last a whole year.
When it comes to protecting your best friend against heartworm disease proheart 6 moxidectin makes it simple.
Dosing information of moxidectin for dogs.
10 moxidectin in glyceryl tristearate microspheres was evaluated in four studies using beagle dogs and one study using ivermectin sensitive collies.
Safety margin was evaluated as 3 treatments of ph 12 0 control.